Dr. Justin M. Miller
Professor | Director, Molecular Biosciences Ph.D.
Departments / Programs
- Department of Chemistry
- Molecular Biosciences, Ph.D.
- Chemistry [M.S.]
- Chemistry
- Biomedical Sciences, M.S.
Degree Information
- PHD, University of Alabama at Birmingham (2013)
- MS, University of Alabama at Birmingham (2011)
- BS, University of Alabama at Birmingham (2008)
Areas of Expertise
Biochemistry/Biophysics, Enzymology, Protein Engineering
Publications
Selected Peer-Reviewed Research Articles
(† Corresponding Author)
- J.D. Marsee, C.A. Brambley, et al., J.M. Miller†. "Expansion and Classification of Poly(Aspartic Acid) Hydrolases through the Identification of Four New PahZ1 Homologs." Protein Engineering, Design, and Selection (2026).
- J.M. Miller† and A. Offenbacher. "Chemical Insights into Enzyme Structure and Function." Frontiers...
Selected Peer-Reviewed Research Articles
(† Corresponding Author)
- J.D. Marsee, C.A. Brambley, et al., J.M. Miller†. "Expansion and Classification of Poly(Aspartic Acid) Hydrolases through the Identification of Four New PahZ1 Homologs." Protein Engineering, Design, and Selection (2026).
- J.M. Miller† and A. Offenbacher. "Chemical Insights into Enzyme Structure and Function." Frontiers in Chemical Biology 4 (2025).
- J. Couch, J.D. Marsee, et al., J.M. Miller†. "Novel DNA-Binding Activity Exhibited by Poly(aspartic acid) Hydrolase-1." Biochemistry (2024).
- B. Anderson, D.L. Bryant, S. Gozem, C. Brambley, S.T. Handy, A. Farone, J.M. Miller†. "Solvent-Dependent Emissions Properties of a Model Aurone Enable Use in Biological Applications." Journal of Fluorescence. (2024).
- R. McGinnis, C.A. Brambley, et al., J.M. Miller, M.D. Gainey†, J.R. Wallen†. "A Monomeric Mycobacteriophage Immunity Repressor Utilizes Two Domains to Recognize an Asymmetric DNA Sequence." Nature Communications (2022).
- C.A. Brambley, et al., J.M. Miller†. "Sphingomonas sp. KT-1 PahZ2 Structure Reveals a Role for Conformational Dynamics in Peptide Bond Hydrolysis." J. Phys. Chem. B (2021).
Peer-Reviewed Book
- J.M. Miller† and J.D. Marsee. Protein-Ligand Binding Thermodynamics. ACS In Focus Series. American Chemical Society (2023).
See Google Scholar Profile for full listing of peer-reviewed publications:
Research / Scholarly Activity
Polymers are essential to life in modern society with critical roles in the production of an array of materials. Unfortunately, their ubiquitous nature has resulted in significant environmental accumulation in our oceans and landfills, which in part is resultant from shortcomings associated with recycling. Recent efforts have pursued biodegradable replacements for traditional petroleum-derived polymers with the primary focus on plastics. While these efforts are warranted, and garner media att...
Read More »Polymers are essential to life in modern society with critical roles in the production of an array of materials. Unfortunately, their ubiquitous nature has resulted in significant environmental accumulation in our oceans and landfills, which in part is resultant from shortcomings associated with recycling. Recent efforts have pursued biodegradable replacements for traditional petroleum-derived polymers with the primary focus on plastics. While these efforts are warranted, and garner media attention because of their visible accumulation, there is an equal necessity to investigate degradation of those polymers we cannot see, water-soluble polymers (WSPs). The Miller laboratory is interested in the development of engineered enzyme tools to degrade WSPs that may occur as environmental pollutants.
Courses
CHEM4500 (Biochemistry 1), CHEM4510 (Biochemistry 2), CHEM4520 (Topics in Biochemistry), CHEM4530 (Biochemical Techniques)
