Recent Peer-Reviewed Publications:

1. R. McGinnis, C.A. Brambley, B. Stamey, W. Green, K. Gragg, E. Cafferty, T.C. Terwilliger, M. Hammel, T. Hollis, J.M. Miller, M.D. Gainey†, and J.R. Wallen†. “A Monomeric Mycobacteriophage Immunity Repressor Utilizes Two Domains to Recognize an Asymmetric DNA Sequence.” Nature Communications. 13, 4105 (2022). .

2. T. Lamantia, A. Jansch, J.D. Marsee, M.H. Weiland, J.M. Miller. “Engineered Sphingomonas sp. KT-1 PahZ1 Monomers Efficiently Degrade Poly(aspartic acid).” Biophys. Chem. 281, 106745. (2022).

3. C.A. Brambley, T.J. Yared, M. Gonzalez, A.L. Jansch, J.R. Wallen, M.H. Weiland, J.M. Miller. “Sphingomonas sp. KT-1 PahZ2 Structure Reveals a Role for Conformational Dynamics in Peptide Bond Hydrolysis.” J. Phys. Chem. B. 125(22), 5722-5739. (2021).

4. C.A. Brambley, A.L. Bolay† , H. Salvo†, A.L. Jansch†, T.J. Yared†, J.M. Miller, J.R. Wallen, and M.H. Weiland. “Structural Characterization of Sphingomonas sp. KT-1 PahZ1 Catalyzed Biodegradation of Thermally Synthesized poly(aspartic acid).” ACS Sustainable Chem. Eng. 8(29), 10702-10713. (2020).

See Google Scholar Profile for full listing of peer-reviewed publications:

Justin M. Miller Google Scholar

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Polymers are essential to life in modern society with critical roles in the production of an array of materials. Unfortunately, their ubiquitous nature has resulted in significant environmental accumulation in our oceans and landfills, which in part is resultant from shortcomings associated with recycling. Recent efforts have pursued biodegradable replacements for traditional petroleum-derived polymers with the primary focus on plastics. While these efforts are warranted, and garner media attention because of their visible accumulation, there is an equal necessity to investigate degradation of those polymers we cannot see, water-soluble polymers (WSPs). The Miller laboratory is interested in the development of engineered enzyme tools to degrade WSPs that may occur as environmental pollutants.

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